Given the age of the meteorite is 4.5 billion years old with 78 atoms of lead-206 the answer should be B. 156. The half-life of uranium-238 in order to decay into lead-206 is 4.46 billion years, which means that the original number of atoms is 156.
Megacity would probably have the biggest affect on the immediate environment and possible the outlands of the megacity as well.