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geniusboy [140]
4 years ago
12

Why is primase required for replication?

Biology
1 answer:
nasty-shy [4]4 years ago
4 0

Primase is a DNA-dependent RNA polymerase. Primase synthesizes the short RNA molecules, or primers, that provide a 3'–OH to which DNA polymerase can attach deoxyribonucleotides in replication initiation. The DNA polymerases require a 3'–OH to which they add nucleotides, and therefore they cannot initiate replication.

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