The free nerve endings
can detect pain, temperature, itch and hair movement. Merkel's disks can detect pressure, position and static touch features. Pacinian corpuscles are sensitive to vibration while Meissner's corpuscles are sensitive to light and touch.
Answer:
1. P120 is degraded in the 26S proteasome
2. The 26S proteasome has a major role in protein degradation and is critical for protein homeostasis
3. Cell cycle and DNA replication are cellular processes regulated by the Ras and NFkB pathways
Explanation:
The proliferation-associated nucleolar protein (p120) is a protein known to be expressed during the interphase of the cell cycle, specifically in G1 and early S phase, where any problem with DNA replication trigger a checkpoint, i.e., a molecular cascade of signaling events that suspend DNA replication until the problem is resolved. In mammalian cells, the 26S proteasome is responsible for catalyzing protein degradation of about 80% (or even more) of their proteins. The 26S proteasome acts to degrade rapidly misfolded and regulatory proteins involved in the cell cycle, thereby having a major role in protein homeostasis and in the control of cellular processes. It is for that reason that inhibitors that block 26S proteasome function have shown to be useful as therapeutic agents in diseases associated with the failure of protein degradation mechanisms (e.g., multiple myeloma). The NF-κB are highly conserved transcription factors capable of regulating different cellular processes including, among others, cellular growth, inflammatory responses and apoptosis. Moreover, the MAPK/ERK pathway is able to transduce different signals received on the cell surface to the nucleus. The MAPK/ERK pathway is activated when a singling molecule binds to a cell receptor which triggers a signaling cascade that ends when a transcription factor induces the expression of target genes, ultimately producing a response in the cell (for example, the progression through the cell cycle).
<span>The answer is letter B. The formation of the three geminal layers and the primitive gut. The formation of gastrula starts when the cells starts folding in blastula slowly forming into a blastopore, that results to a double layer cup cell, forming the geminal layers and the primitive gut </span>
Answer:
2 moles of F
Explanation:
for every molecule of CaF2, without the two atoms of F, CaF2 cannot be formed.
Now we multiply both CaF2 and F by 6.02 X 10^23 to convert CaF2 and F to moles, it will be the same ratio since we multiplied both by the same number
Answer:
The correct answer is option C. "Longer beaks allow the birds to better access seeds in bird feeders".
Explanation:
Since climate change makes more difficult for "<em>Parus major</em>" birds to feed from its primary source of food in gardens, the birds are adapting to access their second source of food, which is the bird feeder. Longer beaks allow the birds to better access seeds in bird feeders, therefore, the birds are developing longer beaks in order to adapt to their new conditions.
