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Norma-Jean [14]
4 years ago
12

A nurse is caring for a client who has diabetes mellitus and is taking pioglitazone. The nurse should plan to monitor the client

for which of the following adverse effects?
a. Tinnitus
b. Insomnia
c. Fluid retention
d. Orthostatic hypotension
Medicine
1 answer:
Anit [1.1K]4 years ago
7 0

Answer:

C. Fluid Retention

Explanation:

Pioglitazone belongs to the family of Thiazolidinediones, they act as ligands of the PPARgamma receptor, a pair of nuclear hormone receptors that participate in the regulation of genes related to the metabolism of glucose and lipids. They are used for patients with DM2, specially those with renal disease, since they do not metabolize in the kidney. Among their therapeutical effects they increase secretion of adiponectine, lower liver fat and redistributes it to the subcutaneal layer of the skin. Their side effects include:

-Hepatotoxicity with increased liver enzymes

- Increase risk of long-term fractures

-Weight gain, due to fluid retention with edema. The edema is formed by intracellular effects by the stimulation of Na + pumps which stimulates the hydrosaline retention.

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Which u.s. state produces the most maple syrup annually?
grandymaker [24]

Answer:

The state of vermont.

Explanation:

5 0
2 years ago
A patient consumes 75% of a bottle of water. The bottle holds 500 millimeters.
Aleks04 [339]

Answer

375 millimeter they consumed. 125 millimeters are left

Explanation

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I hope this helps:)

7 0
3 years ago
There are neurotransmitters that can be both excitatory and inhibitory. Explain how this is possible.
Lady bird [3.3K]

Answer:

The answer to the question: There are neurotransmitters that can be both excitatory and inhibitory. Explain how this is possible, would be, Yes, there are some neurotransmitters such as acetylcholine and dopamine, who have both an excitatory and inhibitory effect in other neurons and in cells, and this happens because of the type of receptors they bind to, and the type of cell where they bind.

Explanation:

Neurotransmitters are the messengers, or communication system that the nervous system in general has with itself and with other systems. There are several types of these, and some work both as neurotransmitters and as hormones as well. How they act, where they act, and what kind of response they elicit, depends entirely on the receptors to which they bind, when they are released by a pre-synaptic neuron. Most neurotransmitters are either excitatory, or inhibitory, and some are known as neuromodulators. However, there are two types known today that work as both excitatory and inhibitory: dopamine and acetylcholine. How can either of these act as each of these? Depends on the receptors present on the post-synaptic neuron, or cell, and depends on the type of cell as well. As soon as these two bind to their appropriate receptors, in a specific kind of cell, they will produce the specific response from the cell, either starting an action potential, ir inhibiting it from happening.

8 0
3 years ago
NEED HELP ASAP!
Sonja [21]

Answer:

a) pupillary constrictor

Explanation:

pupillary constrictor - contraction of the sphincter muscle of the iris in response to a bright light causing the pupil to become smaller light...(contract).

6 0
3 years ago
Cocaine and amphetamines are examples of which category of drugs?
evablogger [386]

Answer:

They are CNS (Central Nervous System) Stimulants

8 0
3 years ago
Read 2 more answers
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