I think it's D. (I'm just guessing)
When it fell most people lost trading routes and trading partners since Rome was a big city and everybody went there to trade
The major factors included freedom as well as a new beginning where people could own land. Most of the land in Europe was owned by Nobility. In Americas, nobody owned anything and thus the people could procure land and start anew having farms and similar.
<span>C. The trade of slaves weakened the rulers.
Portugal </span><span>was able to conquer the kingdom of Congo as the monarchy had an agreement to concede part of the population as slaves, which in years weakened the primary power present at the time, allowing the Europe nation to take advantage of this fact and conquer the country for itself, thanks to the weak primary power present.</span>