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forsale [732]
3 years ago
9

Which clinical step is omitted for biosimilar agents?

Biology
1 answer:
Marysya12 [62]3 years ago
4 0
There are normally four steps to approve (or not ) a medicine:
step 1: it must be proven that this drug is not toxic
step 2: it must be proven that this drug is active on sick people
step 3: it is compared to other drugs which have the same indication
step 4: is the pharmacovigilance. The drug is monitored during all its commercialization.

During the approval of biosimilar agents, step 2 is omitted because we need to establish that there are “no clinically meaningful differences” in the efficacy and safety<span> of the biosimilar when compared to the original, which can be done in step 3.</span>
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Parathyroid hormone is the major regulator of the plasma concentration of__________ ions
photoshop1234 [79]

Answer:

Calcium

Explanation:

Parathyroid hormone (PTH) is a hormone that is secreted by the parathyroid gland. It is the major regulator of the plasma concentration of calcium ions. It regulates calcium ions in the kidney, intestine and bones.

In the kidney, is involved in the re-absorption of calcium in distal ducts and the renal collecting duct, it is also involved in activating the conversion of 25-hydroxy vitamin D into 1,25-dihydroxy vitamin D (calcitriol).

In the intestine,  PTH is involved in the absorption of calcium, by increasing vitamin D production.

In the bone, it helps in regulating calcium levels; when serum calcium level is low, PTH stimulates the activity of the osteoclast, to produce more calcium.

4 0
3 years ago
Autosomes are _______ chromosomes. <br> A. haploid<br> B. homologous<br> C. nonsex<br> D. abnormal
Vera_Pavlovna [14]
<span>Autosomes are non-sex chromosomes, meaning they are non-sex determining chromosomes inside cells. Humans naturally have 46 chromosomes in each body cells; 44 of these are actually autosomes that a person inherits from his/her parents. All persons get 22 autosomes from the mother and the other 22 autosomes will be coming from the father. These autosomes always come in pairs and since everyone has 44 of these autosomes in their cells, it should be noted that there are only 22 types that are obviously numbered from 1 to 22. </span>
6 0
3 years ago
Place the members of an ecosystem in the correct order
Lana71 [14]

Individual, population, community, ecosystem

5 0
3 years ago
Which level of organization includes all the other levels of organization ​
Illusion [34]

Answer:

The level of organization that includes all the other levels of organization is the organism level.

Explanation:

Creatures are made out of various organ frameworks that work together and these frameworks are made out of different organs. Organs are made out of tissues of numerous types, while tissues are made out of different cells that each serve their capacity.

7 0
3 years ago
Which nucleic acid is pictured on the right? Justify
Alchen [17]
Nucleic Acids:
- Uracil
- Adenine
- Guanine
- Cytosine
Explanation:
Since we only have one strand shown, I'm going to assume it is RNA. Both DNA and RNA have nucleic acids, but RNA has 1 different nucleic acid; it replaces Thymine with Uracil. So the 4 nucleic acids are uracil, adenine, guanine, and cytosine.
If the picture shown is a cross-section of DNA, then our 4 nucleic acids are adenine, thymine, guanine, and cytosine.
7 0
3 years ago
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