Native peoples of America had no immunity to the diseases that European explorers and colonists brought with them. Diseases such as smallpox, influenza, measles, and even chicken pox proved deadly to American Indians. Europeans were used to these diseases, but Indian people had no resistance to them.
During the 1790s, the young republic faced many of the same problems that confronted the newly independent nations of Africa and Asia in the 20th century. Like other nations born in anti-colonial revolutions, the United States faced the challenge of building a sound economy, preserving national independence, and creating a stable political system which provided a legitimate place for opposition.In 1790, it was not at all obvious that the Union would long survive. George Washington thought that the new government would not last 20 years. One challenge was to consolidate public support. Only about 5 percent of adult white males had voted to ratify the new Constitution and two states, North Carolina and Rhode Island, continued to support the Articles of Confederation. Vermont threatened to join Canada.
I’m not really sure though
True, Chiang Kai-shek led the Nationalists while Mao Zedong led the Communists
The answer to your beloved question that you have asked this wondrous people is the Overland trail.<span />