It has to have an important lesson the story has to be easy to follow for the age range you’re writing about and illustration has to be high quality.
Strabismus may cause reduced vision, or amblyopia, in the misaligned eye. The brain will pay attention to the image of the straight eye and ignore the image of the crossed eye. If the same eye is consistently ignored during early childhood, this misaligned eye may fail to develop good vision, or may even lose vision.