Answer:
In this study, we tested the effects of NEAA-deprived diets and checkpoint inhibitor anti-PD-1 and anti-PD-L1 in colon cancer using syngeneic mouse model (Balb/c) bearing tumors of mouse colorectal cancer cell line CT-26. Three diets were tested, including a natural rodent diet Teklad ENVIGO Global 16% Protein Rodent Diet (control 1), a formulated NEAA-complete diet COMPLETE (control 2, using amino acid mix in place of protein), and a formulated NEAA-deprived diet FTN203 (treatment, using amino acid mix in place of protein). Both COMPLETE and FTN203 have the same nutritional structures, contain 17% w/w protein equivalent, and are isocaloric. After tumor size-based randomization, these diets were provided to mice ad libitum throughout the whole test. Each of these diets was used alone or combined with anti-PD-1 antibody (i.p., twice per week for 2 weeks) or anti-PD-L1 antibody (i.v., twice per week for 2 weeks).
Explanation:
Answer:
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Explanation:
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Answer:
The unemployment rate does not count it discouraged workers becomes the <em>worse indicator</em> of the state of the economy.
Explanation:
Discouraged workers are essentially unemployed. Such workers have not been able to find employment for a long time and thus became discouraged from employment. They are different from generally unemployed because they are not seeking employment actively. For example, they have alternative sources of income or other assets which let them to stay unemployed.
<u>If these people are not counted in the unemployment rate</u>, the state does not develop a system to bring them back into the active labor force, because they require different approach from generally unemployed. In essence, a state has a number of people who could contribute to the economy otherwise.
