<h2>Option (B) is Right Answer</h2>
Explanation:
(B) bacteria that make insulin for is right answer
- <em>The human insulin gene and embedded into the bacterium Escherichia coli</em> to deliver manufactured <em>"human" insulin</em>
- The develop insulin modestly, the quality that produces human insulin was added to the qualities in an normal E. coli microscopic organisms.An example of microbes is then<em> "infected"</em> with the plasmid, and some of them take up the plasmid and fuse the new quality into their DNA
- <em>A plasmid is a little, round, twofold stranded DNA atom that is particular from a cell's chromosomal DNA</em>
Mosunetuzumab is a T-cell reliant bispecific antibody that binds to CD3 and CD20 to trigger T-cell mediated B-cell death.
However, cytokine release syndrome, which has the potential to limit dose and efficacy, can result from powerful immune stimulation with T-cell focused treatments.
We created a novel mechanistic model of immune and antitumor responses to the T-cell bispecifics (mosunetuzumab and blinatumomab), taking into account the dynamics of B- and T-lymphocytes in circulation, lymphoid tissues, and tumors, in order to better understand the mechanisms underlying safety and efficacy as well as to explore safety mitigation strategies.
Using mosunetuzumab nonclinical and blinatumomab clinical data, the model was created and validated. The initial step-fractionated dose was projected to minimize systemic T-cell activation and cytokine release without impairing tumour response.
Simulations described the mechanisms underlying the observed cell and cytokine (IL6) dynamics. The Phase I clinical study for mosunetuzumab was changed to a step-fractionated treatment schedule as a result of these findings, allowing for the safer administration of greater dosages.
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ATP supplies the energy to produce glucose and other carbohydrates. In the chemical equation for photosynthesis, carbon dioxide and water are converted to glucose and oxygen.