The digestive enzyme, pancreatic lipase, is water soluble and can only work at the surface of fat<span> globules. Digestion is greatly aided by </span>emulsification<span>, the breaking up of </span>fat<span> globules into much smaller emulsion droplets. </span>Bile<span> salts and phospholipids are amphipathic molecules that are present in the </span><span>bile</span>