Answer:
The main function of the RB protein is to inhibit the transition from the G1 to S phase. Its activity depends on its phosphorylation state: if RB is not phosphorylated (active state), it is bound to the transcription factor E2F, preventing its translocation to the nucleus and the activation of genes necessary for DNA synthesis; and if it is phosphorylated, by cyclin-CDK complexes, E2F is released and cell proliferation occurs.
Explanation:
Retinoblastoma (Rb) was the first tumor suppressor described and, as we know today, mutations in its structure determine a large number of cancers. Structurally, we speak of a large and multifunctional protein; which is organized in different domains. The activity of this protein is regulated, mainly, by phosphorylation at multiple sites described over the years and is involved in control mechanisms of the cell cycle, apoptosis and senescence.
Answer:
D
Explanation:
Addition of hydroxide ions will decrease its acidity and make it more basic.
Answer:
Identical shape and structure.
Explanation:
Those organisms that reproduce sexually have high variations and differences between the parent and its offspring. They are not identical to each other because the offspring gains half characteristics from male parent and half from the female parent making it different from its parent. Identical feature is present in the organisms that reproduce through asexually means from only one parent so the identical shape and structure is not the cost of sexual reproduction.
