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mamaluj [8]
4 years ago
15

When two living organisms do something useful for each other

Biology
1 answer:
mariarad [96]4 years ago
5 0
They are in a mutually beneficial or symbiotic relationship.
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Tay Sachs is a disease caused by a mutation in a gene that codes for an enzyme used to break down complex molecules. Patients th
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Answer:

Based on the given information , the cellular structure , which don not function properly in Tay Sachs disease  is <u>Lysosomes </u>

Explanation:

<u>LYSOSOMES -:</u> In many animal cells, a lysosome is a membrane-bound organelle. These are spherical vesicles containing hydrolytic enzymes that can break down many types of biomolecules.  A lysosome, with both its membrane proteins and its lumenal proteins, has a particular composition. There are a number of enzymes in lysosomes, helping the cell to break down different biomolecules that it swallows, including peptides, nucleic acids, carbohydrates , and lipids (lysosomal lipase). For optimal function, the enzymes responsible for this hydrolysis need an acidic environment.

<u>TAY SACHS DISEASE -:  </u>The autosomal recessive disorder Tay-Sachs is caused by mutations in both gene alleles (HEXA) on chromosome 15. HEXA codes for the enzyme β-hexosaminidase A alpha subunit. This enzyme is contained in organelles, lysosomes, which break down large molecules for the cell to recycle.  

Normally, β-hexosaminidase A helps to degrade a lipid called ganglioside GM2, but the enzyme is absent or present only in very small amounts in Tay-Sachs individuals, enabling excessive accumulation of ganglioside GM2 in neurons. In the different types of Tay-Sachs, the progressive neurodegeneration seen depends on the speed and degree of accumulation of GM2 ganglioside, which in turn depends on the amount of functional β-hexosaminidase A present in the body.

Hence , the answer is<u> lysosomes .</u>

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Explanation:

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