Question

The normal prion protein is: Multiple Choice a) bound to the ribosomes of neurons. b) bound to the cell membrane of neurons. c) found in the nucleus of neurons. d) found in the mitochondria of neurons. e) found in the synapse between neurons.

Answer 1

Answer: B) Bound to the cell membrane of neurons

Explanation:

The cellular prion protein (PrPC) is a cell surface protein expressed in a variety of different organs and tissues with high expression levels in the central and peripheral nervous systems.

PrPC attaches to the outer surface of the cell membrane by a glycosylphosphatidylinositol anchor but researchers have proposed roles in cell signalling and formation of synapses.