The answer is c. saturated fat because they are solid at room temp!
Japan has many mountains, thus, the outsiders could not easily enter Japan and Japanese could not leave the country. And, thus the self-isolation was helped by the presence of a mountain terrain. This policy was implemented by Togukawa, who insisted on preventing Japan from foreigners.
I think is the Nullification crisis and the war he fought.
Constantinople was the capitol city of Byzantine Empire .
Answer: Constantinople.