In many cases, the activity of an enzyme is regulated by Negative feedback where the end product acts as a non competitive inhibitor.
In feedback inhibition the end product of a metabolic pathway acts on the key enzyme regulating entry to that pathway, keeping more of the end product from being produced. The feedback inhibition acts at the first committed step of the pathway, meaning the first step that's effectively irreversible. The pathway steps regulated by feedback inhibition are often catalyzed by allosteric enzymes.
It's some change in the conditions around the organism, which the organism can detect and respond to. A change in temperature, more light, or something physically poking the organism are examples.
Uranium Is Made In Fuel Rods In The Reactor Vessel
Nonsense mutations make stop codons. If the mutation is towards the beginning of a gene, then the protein that gets created will be cut short and not function properly. But if it was towards the end, there is still a chance that the protein will still be able to work.
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Nose, Pharynx, Larynx, Tracha, Bronchi and Lungs