Climate changed colder and wetter,people weakened by hunger and were led to diseases
Colbert believed that in trying to prevent wealth from leaving the country, he tried to make France self-sufficient
Postive effects could be that it brings people together, gives them a community for supporting each other, focuses their attention on God. It provides a moral framework, comfort for those in need, the promise of an afterlife... and so on.
Negative effects are that the different religions can be seen to inspire conflict in the world, some might say that they focus people too much on religious things rather than on day to day things (so you lose the plot basically!).
President Jefferson hesitated in
submitting the Louisiana Purchase treaty because he did not want to
violate the Constitutional power granted to him. He was aware that the
Constitution does not specifically allow him to buy land or territory from a foreign
power.