<span>Out of the following
given choices;</span>
mutation
recombination
differentiation
change
<span>The answer is
change and mutation. When there is a mismatch base pair the mismatch repair mechanism
of the polymerase enzyme kicks in. if the mismatch repair is defective, then a mutation will occur at the site of the mismatched base. These mutations can result in
changes in the phenotype of the cell that results
in disease. </span>
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The first organic compounds may have been nucleotides and make up nucleotides. Nucleotides bond together to form RNA or DNA. RNA and DNA make up genetic codes. So all of these make up each other in a sort of chain or order.