Answer:
a small deletion occurs in the nucleotide sequence at the aminoterminal of the gene in the signal sequence
Explanation:
A deletion in the sequence of nucleotide that code for the small signal sequence responsible will affect the release of insulin outside the cells because the signal sequence is responsible for carrying the insulin outside the cells. The cells of pancreas are producing the insulin normally but due to mutation in the signal sequence it can not release out of the cells and accumulate inside the cells.
The result will be two new properly formed strands of replicated DNA.
Answer:
Not using control cases and testing his hypothesis only on one pacient, himself. Not creating or using a method that allowed him to measure the results.
Explanation:
During the investigation Alon had a few methodological flaws. First of all, he based a hypothesis over only one case, his own. He should have tested the product on different pacients under similar circumstances, the more the merrier. Moreover, it is not recommended that the investigator tests the hypothesis on himself, since he can lose perspective.
Second of all, he did not use control cases. This means he should have given placebo pills (pills with no medical effect at all) to a group of pacients without them knowing. Doing this helps eliminating the psicologycal factor of the equation, since pacients have proven to get better, in some cases, just because they thought the medicine would heal them, and not because of the drug itself.
Also, he came to a conclusion based on how anxious and worried he felt after the treatment, but expresses the results with words such as <em>"much more"</em>. In this case he should have created and/or used a method to measure the change in anxiety and how much the pacient worried. For example, before starting the test he could have rated his anxiety level from 1 to 10, and then, done the same thing during and after the treatment was over. By doing this he creates data that can be numerically processed and makes the human subjectivity factor smaller.
They use the algae in the water