Question

When the insertion or deletion of one or more nucleotides (excluding multiples of 3) affects the translation of other codons after that point and/or the protein that is produced, it is considered a(n) ________.
A. nonsense mutation
B. missense mutation
C.frameshift mutation
D.in-frame mutation
E.synonymous (silent) mutation

Answer 1

Answer:

C. frameshift mutation

Explanation:

Frameshift mutation is a type of gene mutation that occurs when one or more nucleotide bases are inserted(added) or deleted (lost) from a DNA strand. This results to a shift or alteration in the reading frame of the codons in the mRNA, hence resulting to wrong placement of amino acids. This kind of mutation alters the amino acid sequence during protein translation.

Frameshift mutations result to deleterious changes amino acid sequence of a protein and can cause diseases like , Crohn's disease and some kinds of cancer.

Answer 2

Answer:

C.frameshift mutation

Explanation:

Mutation is one that describes any heritable change of the base-pair sequence of genetic material of an organism.

The question seeks to examine the knowledge of the concept of the frame shift mutation.

These are fee things to note about the frame shift mutation;

• A frameshift mutation occurs when there is an insertion or deletion of nucleotides that is not multiple of three

• If three nucleotides are inserted it will insert an additional amino acid

• This is the most detrimental mutation

• It will alter the amino acid sequence

• It can change the stop codon to lengthen or shorten the polypeptide.

Frame shift mutation is the type of mutation described in the question.