Leucine is an hydrophobic amino acid and lysine is a basic amino acid. Most of the time, disruption of the normal structure of a protein can occur if the two amino acids substituted have different properties eg chemical properties. Hydrophobic substances normally cluster up within buried sites preventing contact with the fluidic environment while some charged ones are found at the surfaces. Thus substition of leaving which is a hydrophobic amino acid for lysine, a basic amino acid will cause distruption of the normally cluster up buried regions.
DNA is found in the nucleus of a cell in two different forms, depending on whether or not the cell is going through mitosis (cell division). When a cell is not going through mitosis, DNA is in a long, loosely coiled form called chromatin.
Women should stand by at least two months after travel (or 2 months after symptoms started to manifest if they get sick) before trying to get pregnant.The waiting period is longer for men because Zika stays in semen longer than in other body fluids.