In eurkaryotes, the wrapping of DNA around nucleosome introduces negative supercoiling because negative super coil knots have high twisting stress and are less tightly packed.The combine loop of protein [histone] and chromosome is called nucleosome.
Answer:
The correct answer is lysosomes
Explanation:
Tay-Sachs disease is a genetic metabolic disorder in which a lipid called GM2 ganglioside builds in the brain which results in spasticity and death in childhood.
This disease is also known as lysosomal storage disease. Lysosomes are the major organelle that contains enzymes to breakdown molecules. In Tay-Sachs disease deficiency of hexosaminidase A occurs in lysosomes and this enzyme is needed to breakdown fats.
So due to this deficiency, it results in the accumulation of fats in the brain and spinal cord causing Tay-Sachs disease.
Answer:Frameshift mutations are likely to change more than one amino acid, infact a completely irrelevant protein with altered amino acid sequence is produced.
Explanation:
Frameshift mutation is due to addition or deletion of bases. From that point onwards the reading frame shifts, different set of codons read. Frameshift mutations are likely to change more than one amino acid, infact a completely irrelevant protein with altered amino acid sequence is produced.
Frame shift mutation can lead to thalassemia due to premature chain termination and run-on-polypeptude that are non-functional.
You can test the different between using less eggshells and more eggshells and record the data to see which one works better
