Answer:
(C) Aminoacyl-tRNA synthetases have an additional active site that binds to non-cognate tRNAs. The tRNAs that bind to this second active are hydrolyzed and released from the enzyme.
Explanation:
In case of translation, proof reading is done by aminoacyl-tRNA synthetases only. Aminoacyl-tRNA synthetases have two mechanisms to avoid error during translation which are mentioned as under:
<u>(1) Chemical proof reading:</u> Incorrect amino acids rather than being hydrolyzed in catalytic pocket get hydrolyzed in editing pocket and thus they hardly get attached to tRNA.
For example: For distinguishing similar amino acids like isoleucine and valine, isoleucyl-tRNA synthetase uses a second active site which is meant for only valine not for isoleucine. In this particular site, valine which had entered the enzyme is cleaved away with the help of editing reaction after which the enzyme is well prepared to process isoleucine which is the correct amino acid for this enzyme.
<u>(2) Kinetic proof reading: </u>Even if an incorrect amino acid has entered a particular aminoacyl-tRNA synthetase, it does not cause appropriate conformational change in the enzyme because of which the incorrect amino acid loosens from the enzyme and does not get incorporated.
Note: In this example, only chemical proof reading is mentioned not kinetic proof reading.
It might be stated that his reliability might be compromised because he writes the story many years later and his memories may be skewed. he is the narrator and the protagonist of the story and it is written in first person so he retells what he remembers from his life experience since he was a child.
Answer:
Numbers 5, and I think 2 the rest are bases
Explanation: * Remember H+ is acids and OH- is base :)
Answer:
The geocentric model says that the earth is at the center of the cosmos or universe, and the planets, the sun and the moon, and the stars circles around it. The early heliocentric models consider the sun as the center, and the planets revolve around the sun.
Explanation:
