Answer and explanation;
-The insulin receptor itself has decreased kinase activity leading to fewer binding sites for singling effectors to become activated.
Therefore; the signaling effectors are less likely to be activated.
-Additionally,, feedback inhibition decreases signaling effector binding to receptor.
-The lack of activation of these initial signaling effectors prevents any subsequent steps from happening.
-We can thus conclude this by saying that higher insulin concentrations are necessary to obtain the same level of signaling leading to physiological effects that would exist in someone without type-2 diabetes.
-Also the requirement for higher insulin concentration means that the cells that respond to insulin are resistant to its effect.
Answer: the tundra is important to protect is that it serves as a habitat for migratory populations, like waterfowl, shorebirds, caribou and several bear species. It is home to endangered animals such as the Arctic Fox, Polar Bear, Grizzly Bear, Caribou, and Musk Ox.
Explanation:
Answer: C
Explanation: Cells reproduce and divide through a process called mitosis