Systemic lupus erythematosus (SLE) is a rheumatic disease attributed to autoimmune mechanisms.
Systemic lupus erythematosus (SLE, lupus) is characterized by a global loss of self-tolerance with activation of autoreactive T and B cells, leading to the production of pathogen autoantibodies and tissue damage.
Innate immune mechanisms are required for aberrant adaptive immune responses in SLE. Recent advances in basic and clinical biology have shed new light on the disease mechanisms of lupus. This review article describes recent studies that provide valuable insights into disease-specific therapeutic targets.
Systemic lupus erythematosus (SLE or lupus) is a systemic autoimmune disease with inflammation of multiple organs. SLE is characterized by the production of pathogenic autoantibodies against nucleic acids and their binding proteins, reflecting a global loss of self-tolerance.
Loss of tolerance with subsequent immune dysregulation is the result of genetic factors in the context of environmental triggers and stochastic events, with recent studies implicating more than 30 genetic loci in disease pathogenesis.
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The inguinal region is inferior to the cervical region
Please write your question properly
Answer:
It is TRUE that In the Harvard alumni study, Paffenbarger reported that individuals who burned fewer than 1,000 calories per week during exercise had nearly twice the mortality risk as those who burned more than 2,500 calories per week
Explanation:
Ralph S. Paffenbarger, Jr. was an epidemiologist, ultramarathoner, and professor at both Stanford University School of Medicine and Harvard University School of Public Health.
A calorie is a unit of energy. In nutrition, calories refer to the energy people get from the food and drink they consume, and the energy they use in physical activity. Calories are listed in the nutritional information on all food packaging. Many weight loss programs center around reducing the intake of calories.
The risk of mortality provides a medical classification to estimate the likelihood of in-hospital death for a patient.
