Answer:
Causal association is defined as two events in which one event leads to the cause/development of the second event such as the consumption of trans-fats and the onset of heart disease. In order to show the causal association, it is necessary to ensure that the 3 criteria of temporality, consistency, and strength are satisfied with respect to the relationship between consumption of trans fats and heart disease. According to this example involving the relationship between trans-fats and heart disease, temporality could be satisfied if one is consuming an excessive amount of foods containing trans-fats such asFrench fries, and who then ends up suffering from heart disease. In order to fulfill the criteria of strength, statistical tests would need to be performed in order to establish that there is a positive correlation between the individuals who consume trans-fats 10 times per week are shown to develop and require treatment for heart disease 90% of the time. Lastly, consistency may be fulfilled by showing that the same results are occurring despite applying the same testing measures on different groups of individuals during various increments. By applying the same tests on different groups, the chances of creating false-positives within the study can be significantly lowered. Numerous studies can be used to determine whether meaningful statements regarding the causal relationship between two factors can be established. By performing multiple studies on individuals’ eating habits and their health outcomes, researchers may then determine whether a relationship exists between the health challenges that they are faced with and the items that they consume.
Explanation:
Answer:
It is important to use the regulatory sequence of a milk gene when constructing a recombinant gene used to produce a human protein secreted in milk because<em> it is capable of increasing or decreasing the expression of specific genes within an organism.</em>
Explanation:
<em>Regulatory Sequence</em> is<em> a segment of a nucleic acid molecule</em> which is capable of increasing or decreasing the expression of specific genes within an organism. Regulation of gene expression is an essential feature of all living organisms and viruses.
Human monoclonal antibody (mAbs) are emerging in the field of cancer therapy and have become an increasing proportion of new drugs that are recently approved. Although there are some methods to obtain antigen-specific mAbs from human B cells, it is generally impossible to directly immunize human beings with antigens of interest. For example, for infectious agents, those approaches are largely restricted. To solve these obstacles, two main approaches have been developed; either by humanizing antigen-specific antibodies from small experimental animals (which is laborious due to the great genetic differences from humans) or rely on the in vitro selection of antigen-specific binders from human antibody repertoires. However, the human mAbs developed by these methods are usually with low affinity.
We are now coming up with a much better idea that is humanizing non-human primates mAbs instead of murine mAbs. Due to the close genetic relationship with humans, immunized NHPs have more potential to be isolated with high affinity antibody to human target than other experimental species, such as mouse, rat and rabbit. In addition, with appropriate method, NHP antibodies are much<span> easier to be humanized</span> without any loss of affinity compared to widely used murine antibodies.
Resource: http://www.creative-biolabs.com/High-Affi-TM-Human-Antibody-Discovery.html
Answer:
C
Explanation:
You do this thing that is this that you have to do by doing that thing with the things so you get a thing. Got it?