A disturbance would be things like lava, flows, newly formed sand dunes, or rocks left from a retreating glacier. These are disturbances because Primary Successions happen in lifeless areas, which soil is incapable of sustaining life.
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Cells placed in a hypotonic solution will take in water across their membrane until both the external solution and the cytosol are isotonic. A cell that does not have a rigid cell wall, such as a red blood cell, will swell and lyse (burst) when placed in a hypotonic solution.
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The second line of defence is nonspecific resistance, which kills intruders in a broad manner without focusing on specific individuals: phagocytic cells ingest and kill any germs that enter body tissues.
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Data would support your hypothesis