I believe it would be refuse but i could be wrong. Hope this helps!
Vasco de Gama was a Portuguese explorer who voyages to India opened up the sea route from western Europe to the East by way of the Cape of Good Hope.
Tiber River. The most important river in central Italy. It runs some 400 kilometers through a long valley running from Tuscany through Umbria, Latium, past Rome, to the Tyrannize Sea at Ostia (literally, the “mouths” of the river). The river had a positive as well as negative impact on the development of Rome.
The Mediterranean Sea was important to the Roman Empire in that it was a vital trade link with other parts of the Empire, especially the Middle East and North Africa. ... The Romans referred to it as "their sea" and would not allow competing empires to flourish on it, such as the Greeks and Egyptians.