The answer is A, C & D make no sense. B is not wrong, but A is the better answer.
August 2, 1776 at the Pennsylvania State House, Independence Hall in Philadelphia, Pennsylvania.
It was signed on August 2, 1776 at the Pennsylvania State House in the Independence Hall. (In Philadelphia, Pennsylvania)
Interesting fact: Philadelphia means "the city of brotherly love" and Pennsylvania was named after William Penn, and means "the forests of Penn."
In general, it was people from Portugal who first shipped enslaved Africans to the New World. Although it should be noted that the British and the French soon followed suit.