Question

Based on the pedigree that is shown above, how to describe Fred?

Answer 1

Answer:

The given pedigree analysis shows sex-linked trait where the female work as a carrier and have X linked recessive gene that is $X^{h}$ and the male is normal.

So, Fred will be a male with $X^{h}$$Y$ gene and Fred will be affected with X linked disease which is carried by female.

If,  $X^{h}$ gene in the female (Ann)  act as a carrier of hemophilia and the male (John) is normal, then Fred will be a male affected with hemophilia (sex linked disease).

Hence, Fred will be affected male with  $X^{h}$$Y$ genotype.