The correct option is E: "refocusing the existing businesses on new substitute product-line opportunities outside the existing industry framework."
Explanation:
To boost the combined performance of a collection of businesses from an organization needs strategic decision to be made. These decision should focus on Entering into new industries, reducing the business portfolio to eliminate some business, pursuing newer opportunities in line with the business, and in some cases a restructuring might be needed to improve the overall performance of a business. However it is not a strategic development decision to change the entire focus of the business on a new-substitute product line outside the business framework. This makes no sense as it involves a totally different approach, maybe staff, and strategy capable of causing business collapse.
Efficacy is defined as the ability to produce a desired or intended result. Celia's focus is to determine the ability of certain programs to produce a desired result, and that is to develop a vocabulary that will set them up for success in kindergarten.