For me, the divide between the Middle Ages and the Renaissance has long been the invention of the printing press by Gutenberg.
With the invention of the printing press, documents began to be much more widely available.
The impact of this was that the attitude towards the Church shifted dramatically from the Middle Ages to the Renaissance as people began getting access to more documents and used those documents to think critically about the Catholic Church and its practices.
So, by the time of Luther, there was a fervent group of informed and educated reformers who were influenced by Renaissance views on critical thinking who took issue with the sale of indulgences in a way that was not done during the Middle Ages.
Answer:
C. The relationship between the federal government and state governments is specifically laid out in the constitution
In the midle of the 1700s, the British, especially the fur traders moved into Ohio River Valley and claimed the land from French fur traders and Indians. The British want to expand fur trade with the indians, and to take business away from their rivals. So that was the main reason.
This might not be the right one but I think its the first one...........................