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skelet666 [1.2K]
3 years ago
9

If all glucose is normally reabsorbed in the proximal tubule of the nephron, why do people with diabetes have glucose in their u

rine
Medicine
1 answer:
Svetlanka [38]3 years ago
8 0

Answer:

People have glucose in their urine because they reach very high glucose values, that is, glycemic peaks.

Glycemic peaks occur due to a functional lack of the hormone insulin, insulin in this pathology is altered or absent, that is why the cells cannot assimilate energy and glucose does not enter the intracellular medium.

When glycemia reaches very high values, it is secreted by urine, but not all glucose is secreted, that is why high concentrations of glucose will be found in plasma and urine, this is called glycemia or uremia in the case of urine.

Diabetes disease is discovered by laboratory tests and clinical signs, the most frequent are: high blood glucose, glycosylated hemoglobin, uremia, high concentration of ketone bodies or ketoacidosis, ketone breath, alteration of the cardiovascular system, high cholesterol, weakness or fatigue, spontaneous diarrhea, among others.

Explanation:

The nephron is the glomerular filtration unit, in which a filtering of the body's waste takes place, through channels or diffusion waves, these channels or these diffusion mechanisms, some are non-saturable and others are saturated in the face of extreme concentrations, That is why, in the event of glycemic peaks, the nephron is highly demanded to eliminate glucose, and the mechanism of excision by urine could even be oversaturated.

People who suffer from diabetes can be for various reasons, genetic causes, obesity, ideopathic, autoimmune disorders or even due to genetic failure in the formation of the hormone insulin.

The only effective method to be able to regulate this imbalance and help the nephron to eliminate it correctly is by giving the patient injectable insulin or oral hypoglycemic agents.

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