Answer:
The correct answer is option C.
Explanation:
As the proteins are produced in the endoplasmic reticulum membrane, they amalgamate with the vesicles and then they are conducted towards the membrane's cell surface where they act as an integral membrane protein.
The outer end will bind with the ligand and the other one will get attached towards the cytoplasm. Thus, the pinsulin in the given case will combine with the C terminus of the protein.
This process is called osmosis whereby water exits the cell through its selectively permeable membrane and into the salt solution to dilute and balance the pressure caused by the concentrated salt solution.