Answer:
These molecules are referred to in biology as the molecules of life. ... Without any of these four molecules, a cell and organism would not be able to live. All of the ... Many organisms have what is known as a cell wall that surrounds their cell. ... There are two types of nucleic acids that are essential to all lif
Explanation:
If thousands of glucose molecules were bonded together with equal numbers of sucrose molecules, the resulting substance could be described as a polysaccharide. They are <span>polymeric carbohydrate molecules composed of long chains of monosaccharide units bound together by glycosidic linkages.</span>
Answer:
One of the common genetic disorders is sickle cell anemia, in which 2 recessive alleles must meet to allow for destruction and alteration in the morphology of red blood cells. This usually leads to loss of proper binding of oxygen to hemoglobin and curved, sickle-shaped erythrocytes. The mutation causing this disease occurs in the 6th codon of the HBB gene encoding the hemoglobin subunit β (β-globin), a protein, serving as an integral part of the adult hemoglobin A (HbA), which is a heterotetramer of 2 α chains and 2 β chains that is responsible for binding to the oxygen in the blood. This mutation changes a charged glutamic acid to a hydrophobic valine residue and disrupts the tertiary structure and stability of the hemoglobin molecule. Since in the field of protein intrinsic disorder, charged and polar residues are typically considered as disorder promoting, in opposite to the order-promoting non-polar hydrophobic residues, in this study we attempted to answer a question if intrinsic disorder might have a role in the pathogenesis of sickle cell anemia. To this end, several disorder predictors were utilized to evaluate the presence of intrinsically disordered regions in all subunits of human hemoglobin: α, β, δ, ε, ζ, γ1, and γ2. Then, structural analysis was completed by using the SWISS-MODEL Repository to visualize the outputs of the disorder predictors. Finally, Uniprot STRING and D2P2 were used to determine biochemical interactome and protein partners for each hemoglobin subunit along with analyzing their posttranslational modifications. All these properties were used to determine any differences between the 6 different types of subunits of hemoglobin and to correlate the mutation leading to sickle cell anemia with intrinsic disorder propensity.
Explanation:
When the number of phytoplankton drastically decreased, this would affect the entire food web.
Phytoplankton are plankton consisting of microscopic plants. They are the autotrophic components of the plankton community and a key part of oceans, seas and freshwater basin ecosystems.
