The allele for dwarfism - D its dominant
Recessive allele -d
If the person has heterozygous alleles -Dd the person will have achrondroplastic dwarfism
However if the person if homozygous for the allele DD it’s Lethal and person can’t survive
If both parents are Dd
Dd X. Dd
Offspring DD Dd Dd dd
Probability of children who survive with the trait have the genotype Dd
Probability - 1/4 + 1/4
Probability of having surviving children with the trait -1/2 -0.5
Answer:
For both actin and microtubule polymerization, nucleotide hydrolysis is important for decreasing the binding strength between subunits on filaments.
Explanation:
Cytoskeletal filaments are common to eucaryotic cells and are impotartant to the spatial organization of cells. Intermediate filaments provide mechanical strength and resistance to shear stress. Microtubules determine the positions of membrane-enclosed organelles and direct intracellular transport. Actin filaments determine the shape of the cell's surface and are necessary for whole-cell locomotion. A large number of accessory proteins are present that link the filaments to other cell components, as well as to each other. Accessory proteins are essential for the assembly of the cytoskeletal filaments in particular locations, and it includes the motor proteins that either move organelles along the filaments or move the filaments themselves.
Actin filaments and microtubules are assembled with expenditure of energy i.e the ATP/GTP tightly bound to actin/tubulin is irreversibly hydrolyzed to ADP/GTP during the assembly process, and liberation of Pi in the medium occurs subsequent to the incorporation of subunits in the polymer. Pi release acts as a switch, causing the destabilization of protein-protein interactions in the polymer, therefore regulating the dynamics of these fibres. The progress is made in four areas: the chemistry of the NTPase reaction; the structure of the intermediates in nucleotide hydrolysis and the nature of the conformational switch; the regulation of parameters involved in dynamic instability of microtubules; and the possible involvement of nucleotide hydrolysis in the macroscopic organization of these polymers in highly concentrated solutions, compared with the simple case of a equilibrium polymers.
Adenosine monophosphate (AMP) is a regulatory molecule in metabolic processes such as glycolysis and gluconeogenesis. For example, it stimulates the glycolytic enzyme phosphofructokinase, and therefore ATP production, and it inhibits the gluconeogenic enzyme fructose 1,6-bisphosphatase. Adenylate kinase catalyzes the reversible reaction shown here:
2ADP --> ATP + AMP
During periods of intense activity, when glycolysis is used in the generation of ATP, the reaction lies to the right, decreasing [ADP], generating ATP, and accumulating AMP. However, [ATP] is usually much greater than [ADP], and [ADP] is greater than [AMP].
Determine [AMP] when 3% of the ATP in a hypothetical cell is hydrolyzed to ADP.
<span>In this cell, the initial concentration of ATP is 265 ?M, and the total adenine nucleotide concentration (the concentration of ATP, ADP, and AMP) is 368 ?M. The equilibrium constant K is 0.82</span>
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Answer: a close evolutionary connection between humans and many other mammals
Explanation:
