Question

Compare and contrast characteristics of X-linked dominant and X-linked recessive inheritance patterns.

Answer 1

Answer:

X linked dominant disorders are caused when the genes on the X chromosomes gets mutated. X linked dominant disorders phenotype is observed in each generation and males experience more severe symptoms of disorder as compared to a female.

In X linked recessive disorder one copy of affected X gene is sufficient to cause the disease in males. In case of females both the X gene are required to be effected for causing disease.

Explanation:

X linked dominant disorders are caused when the genes on the X chromosomes gets mutated. X linked dominant disorders phenotype is observed in each generation and males experience more severe symptoms of disorder as compared to a female. This disorder is never transmitted to male child by the father or in other way we can say that there is no male to male transmission. For example Fragile X syndrome

In X linked recessive disorder one copy of affected X gene is sufficient to cause the disease in males. In case of females both the X gene are required to be effected for causing disease. Males are more affected by this disorder as compared to females. For example - hemophilia . This disorder is never transmitted to male child by the father just like the X linked dominant disorder or in other way we can say that there is no male to male transmission.