The correct answer would be D), over millions of years, Pangaea broke apart and drifted to form the seven continents.
The effect differs. It could produce a different amino acid in the sequence because the corresponding codon has changed. It could also prevent the production of the originally intended sequence by changing one of the amino acids of a "start" codon (aka AUG) or extend the protein's sequence by modifying a "stop" codon (UAA, UAG, UGA or UGG), producing a new protein that might be useless or have different effects on the cell.
The correct answer for the given statement above would be true. Yes, it is true that local topography and sea surface temperature contribute to differences in climate between various localities. In fact, these factors contribute largely towards variations in the climate of places. Hope this answers the question.
Genetic drift is the dramatic almost sped up process of natural selection due to the untouched habitat the species I lives in. Genetic drift is characterized by the changing in alleles, whether more or less, natural selection could care less as long as they're creating diverse populations.