A major Renaissance work by Machiavelli was The Prince.
Explanation:
Nicolás Machiavelli was an Italian diplomat, civil servant, political philosopher and writer, considered father of modern Political Science. He was also a relevant figure of the Italian Renaissance. In 1513 he wrote his treatise on political doctrine entitled The Prince, posthumously published in Rome in 1531.
The Prince is sometimes said to be one of the first works of modern philosophy, especially political philosophy, in which effective truth is considered to be more important than any abstract ideal. It was also in direct conflict with the dominant Catholic and scholastic doctrines of the time with respect to politics and ethics.
The American Revolution was principally caused by colonial opposition to British attempts to impose greater control over the colonies and to make them repay the crown for its defense of them during the French and Indian War (1754–63)