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andrew11 [14]
4 years ago
15

What was the purpose of adding methotrexate to the cells expressing a genetically-engineered Dihydrofolate Reductase enzyme in t

he mitochondrion-targeting experiment we discussed in lecture?
Biology
1 answer:
ira [324]4 years ago
5 0

Answer:

Methotrexate inhibits the synthesis of DNA, RNA, and protein synthesis of the cells in the experiment.

Explanation:

Methotrexate competitively inhibits the enzyme dihydrofolate reductase (DHFR) which is involved in the synthesis of tetrahydrofolate from the inactive dihydrofolate. The methotrexate blocks the enzyme by binding to its active site thereby preventing further reaction of the dihydrofolate reductase enzyme and dihydrofolate. Tetrahydrofolate is a useful material for the de novo synthesis of thymidine, a nucleoside. And without thymidine, DNA synthesis is hindered. Methotrexate therefore inhibits the synthesis of DNA, RNA, thymidylates and of course protein synthesis.

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How can reproductive barriers form sympatric populations while their members remain in the same geographic area?
grandymaker [24]

Answer: Polyploidy

Explanation:

Polyploidy is defined as the phenomenon by which cells, tissues or organisms with three or more complete sets of chromosomes originate. Such cells, tissues or organisms are called polyploids.

If the genomes of a polyploid species come from the same ancestral species, it is said to be autopolyploid or autoploid. And if they come from two different ancestral species, it is said to be allopolyploid or alloploid. <u>Depending on the number of complete chromosome sets that the species has it is called triploid (3X), tetraploid (4X), pentaploid (5X), hexaploid (6X) and so on, where X is the monoploid number, and not to be confused with the haploid number. </u>

Redundant genetic elements of polyploid organisms can be transformed into single copies by sub-functionalization, neofunctionalization mechanisms or by the appearance of certain mutations.

<u>Two populations are sympatric when they exist in the same area and thus frequently encounter one another. </u>In general, different species cannot interbreed and produce healthy and fertile offspring due to barriers known as reproductive isolation mechanisms.  Polyploidy speciation is common in plants but rare in animals. So, animal species are much less tolerant of changes in ploidy. For example, human embryos that are triploid or tetraploid are not viable, cannot survive.

4 0
3 years ago
Use the drop-down menus to complete each statement.
sp2606 [1]

Answer:

<h2>Use the drop-down menus to complete each statement.</h2>

1. bureau of land management

2. U.S fish and wildlife service

3. U.S fish and wildlife service

4. bureau of land management

5. National park service

Explanation:

Hope it is helpful....

4 0
3 years ago
Read 2 more answers
How do saturated fats differ from unsaturated fats?
Andrews [41]
Saturated fats are solid at room temperature, while unsaturated are liquid at room temperature. hope this helped
5 0
3 years ago
What would you expect to happen to a plant as temperature and precipatiom increases? Write your claim and evidence!!
Anon25 [30]

Answer:

Both have great effect on plant when increases from a certain limit.

Explanation:

When the temperature falls in the optimum range it has a good effect on plants growth because the rate of photosynthesis is maximum. Precipitation also has a great effect because it provides water that is necessary for the plants. If the temperature increases from a certain limit, it burns plant body and decreases photosynthesis whereas if precipitation increases it causes flood condition which kills the plant due to removal from the soil.

3 0
3 years ago
PLEASE HURRY!!!
kvasek [131]

B) Frost


Frost is a thin layer of ice on a solid surface, which forms from water vapor in an above freezing atmosphere coming in contact with a solid surface whose temperature is below freezing, and resulting in a phase change from water vapor to ice as the water vapor reaches the freezing point.


3 0
4 years ago
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