Your aging aunt luella has has a series of small strokes. these strokes can progressively damage her brain and are most likely to produce dementia
Protein-protein interactions within the CARMA1-BCL10-MALT1 complex:
- The T-cell receptor and B-cell receptor-dependent NF-B induction and lymphocyte activation are mediated by the CBM complex, which is made up of the proteins CARMA1, BCL10, and MALT1.
- Each of the proto-oncoproteins CARMA1, BCL10, and MALT1 is a somatic gain-of-function mutation or chromosomal translocation, and dysregulation of CBM signaling is a characteristic of numerous lymphoid malignancies, including Activated B-cell Diffuse Large B-cell Lymphoma.
- Moreover, a number of immunological dysregulation diseases have been linked to both gain- and loss-of-function germline mutations in CBM complex proteins.
- Over the past ten years, careful examination of the interactions of CBM components has yielded a wealth of detailed structural knowledge.
- Here, we discuss important discoveries about the molecular nature of these protein-protein interactions that have helped the research develop a detailed understanding of how these proteins come together to form high-order filamentous CBM complexes.
- Approaches to therapeutic suppression of the CBM complex have thus far centered on obstructing MALT1 protease activity in order to treat lymphoid malignancy and/or autoimmunity.
- The structural effects of MALT1 protease inhibitors on significant protein-protein interactions are also reviewed in detail.
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Answer:
I believe the correct answer would be D- Plant cell do not have cytoplasm
Explanation:
Plant and animal cells both have a cytoplasm so D is the incorrect statement.
Answer;
-5.83 AU
Explanation;
A year is defined as the time it takes a planet to complete one revolution of the Sun, for Earth this is just over 365 days. This is also known as the orbital period. Unsurprisingly the the length of each planet’s year correlates with its distance from the Sun.
Using the equation;
t² = a³
t = 3.24 years, the time it takes the planet to orbit .
a (astronomical units) = 3.24 ^3/2
= 5.83 anatomical units (AU).
Answer:
(1) the reproduction of an entire unicellular organism, (2) the growth and repair of tissues in multicellular animals, and (3) the formation of gametes (eggs and sperm) for sexual reproduction in multicellular animals.
Explanation:
