The Black Death resulted in the deaths of an estimated 75-200 million people—approximately 30% of Europe's population. ... The Great Famine of 1315-1317 and subsequent malnutrition in the population likely caused weakened immunity and susceptibility to disease.
The Black Death spread from central Asia using rats as infection vectors. It resulted in around 100-200 million European deaths, which was 30% of the continents population at the time. The Great Famine of 1315 also caused millions of deaths in a span of two years as a result of failed crop growths. Europe hadn't recovered from this economic and societal damage until 1322.
