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DIA [1.3K]
3 years ago
7

Chain of hemoglobin is 1 m.u. from the albino locus. assume for the moment that the same is true in humans. the disease sickle-c

ell anemia is the result of homozygosity for a particular mutation in the β-globin gene.
Biology
1 answer:
sergeinik [125]3 years ago
3 0
*Sickle cell disease is a constitutional corpuscular hemolytic anemia related to an abnormal structure of the globin chain. It is an autosomal recessive disease, which means homozygosity is necessary to fully express the illness.
*It corresponds to the synthesis of an abnormal hemoglobin, HbS, which is different from normal Hb (HbA).

*The S allele (located in the chromosome 11), responsible for the anomaly, is especially widespread in the African continent, it is also found in other regions of the Mediterranean.
<span>
*Mutation GAG to GTG
leading to the substitution Glutamine by a valine in position 6 of the chain of the globine.</span>
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