It can be expected that there
will be closure of the patent ductus arteriosus for this is the effect of
indomethacin. The adverse effect would include platelet dysfunction, decrease
gasto-intestinal motility and an increase in necrotizing enterocolitis. With this,
the nurse should anticipate the possible outcomes where there will be increase
bleeding time and decrease gastro-intestinal function after giving
indomethacin.
The reactants of photosynthesis are water, carbon dioxide and light energy.<span>Plants use these reactants to make the food that is essential for plant growth.</span>
Answer and Explanation:
Ribosomes are the primary structure for protein synthesis. They can be found in the rough endoplasmic reticulum or floating in the cytosol.
Free ribosomes are not attached to any cytoplasmic structure or organelle. They synthesize proteins only for internal cell use. Other ribosomes are attached to the membrane of the endoplasmic reticulum and they are in charge of synthesizing membrane proteins or exportation proteins. Free and attached ribosomes are identical and they can alternate their location. This means that although free ribosomes are floating in the cytosol, eventually, they can get attached to the endoplasmic reticulum membrane.
Synthesis of proteins that are destined to membrane or exportation starts in the cytoplasm with the production of a molecule portion known as a <u>signal aminoacidic sequence</u>. This signal sequence varies between 13 and 36 amino acids, is located in the <u>amino extreme</u> of the synthesizing protein, and when it reaches a certain length, it meets the <u>signal recognizing particle</u>. This particle joins the signal sequence of the protein and leads the synthesizing protein and associated ribosome to a specific region in the Rough endoplasmic reticulum where it continues the protein building. When they reach the membrane of the endoplasmic reticulum, the signal recognizing particle links to a receptor associated with a pore. Meanwhile, the ribosome keeps synthesizing the protein, and the enlarged polypeptidic chain goes forward the reticulum lumen through the pore. While this is happening, another enzyme cuts the signal sequence, an action that requires energy from the ATP hydrolysis. When the new protein synthesis is complete, the polypeptide is released into the reticulum lumen. Here it also happens the protein folding (which is possible by the formation of disulfide bridges of proteins are formed) and the initial stages of glycosylation (the oligosaccharide addition).
Once membrane proteins are folded in the interior of the endoplasmic reticulum, they are packaged into vesicles and sent to the Golgi complex, where it occurs the final association of carbohydrates with proteins. The Golgi complex sends proteins to their different destinies. Proteins destined to a certain place are packaged all together in the same vesicle and sent to the target organelle. In the case of membrane proteins, they are packaged in vesicles and sent to the cell membrane where they get incrusted.
There are certain signal sequences in the <u>carboxy-terminal extreme</u> of the protein that plays an important role during the transport of membrane proteins. A signal as simple as one amino acid in the c-terminal extreme is responsible for the correct transport of the molecule through the whole traject until it reaches the membrane.
Transfer of newly created plasmids to e coli. The bacteria that contains a plasmid with antibiotic resistance will grow in the presence of antibiotic concludes that the insertion was successful.
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<u>Explanation:</u></h3>
The plasmid DNA that contains the foreign DNA when integrated with the competent bacteria which is e coli and heated, plasmid DNA will be entering into the bacteria by means of some smaller pores that are created in the membranes of the cell.
The plasmid DNA will be copied many times with the help of the replicating mechanism of DNA of the bacteria. Bacteria will grow on a nutrient rich food called agar after the transformation process. Those bacteria that contains a plasmid containing antibiotic resistance only grow in the antibiotic presence. Transformed bacteria will then grow in larger quantity.
The body's first line of defense against pathogens are mucous membranes, as they prevent bacteria from entering the body. Hope this helps!
