DSM is a diagnostic and statistical manual made by the American Psychiatric Association to define how the diagnosis of mental disorders is made. Used by psychologists, doctors and occupational therapists.
ICD determines the classification and coding of diseases and a wide variety of signs, symptoms, abnormal findings, complaints, social circumstances and external causes of damage and / or disease
Please be more specific and give more details to the question
I believe the answer is: His second treatise on government explained the social contracy theory of government and led to several revolutions.
According to john locke's social contract, if the government somehow fail to secure the natural rights and will of the citizens, than the citizens should have the power to change the leadership through legal methods. Which can we see in the democratic system today.