Answer:
The correct answer would be D) tissue.
In biology, the level of organisation from simplest to complex level can be summarized as:
Organelles → cells → tissues → organs → organ systems → organisms → populations →communities → ecosystem → biosphere.
It is clear that tissue is organization level that exists between cells and organs.
When similar cells are assembled together to perform specific function, the assembly or this organization is said to be the tissue.
There can be different types of tissues such as muscle tissue, nerve tissue et cetera.
Similarly, tissues arrange themselves to carry out specific function in the form of organ.
For example, heart is made up of cardiac tissue.
Answer:
Explanation:
Pharmacophore (pharmacology) - The molecular framework responsible for a drug's biological activity. According to IUPAC — A pharmacophore is the ensemble of steric and electronic features that is necessary to ensure the optimal supramolecular interactions with a specific biological target structure and to trigger (or to block) its biological response.
Privileged structures are defined as molecular frameworks which are able of providing useful ligands for more than one type of receptor or enzyme target by judicious structural modifications.
1) The 1,4-dihydropyridine ring is present in many biologically important molecules that acts as an important scaffold for cardiovascular drug - a calcium antagonists and although it is technically not considered as a pharmacophore, it is considered as a privileged structure.
1,4-Dihydropyridine (DHP), belongs to the class of calcium antagonist that inhibits the influx of extracellular Ca+2 through the L-type voltage-dependent calcium channels.
A positional substitution in the 4-position is feasible in the heterocyclic ring which in turn culminates in various calcium channel antagonist activities and this heterocyclic ring is the common feature for various pharmacological activities such as anti-inflammatory activity, analgesic activity,
antihypertensive, antianginal, antitumor, antitubercular activity and antithrombotic .
Position on the heterocyclic ring binds to the L-type channel and also to N-type channel on membranes.
2.) The bioisosteres are not a suitable bioisostere for the traditional C-4 aryl or heteroaryl substitution which is necessary for calcium ion blockage thereby inhibiting it to function with the mechanism shared above.
Answer:
Scientists often use models of Earth to study the movement of earth and it's moon. They figure out what the distance is from the moon to the point between earth and moon where the gravitational pulls of earth and moon are equal.
Because high estrogen halts bone growth
Answer:
below(sorry if i'm wrong, it's been a little while)
Explanation:
deletion
substitution
insertion
inversion
duplication
translocation ?
