Dihydrofolate reductase is an enzyme that reduces dihydrofolic acid to tetrahydrofolic acid. Methotrexateis its inhibitor. It interferes with folate metabolism by acting as a competitive inhibitor of the enzyme.
Since folateis necassary for rapid dividing cells, such as cancer cells, methotrexate can be used as anticancer drug that inhibits DHFR.
The three parts of the cell theory are: cells are the smallest unit of life; all cells come from preexisting cells; and living thing is made up of one or more cell.
