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Answer:
In p53 pathways, 3 proteins which are mutate and cause cancer that proteins are:
1.BRCA2
2. p53 in Rb genes binds with deoxyribonucleic acid that stimulates another gene to produce a protein known as p21 that interacts with cdk2. When p21 is combined with cdk2 cell will not pass through to the next stage of cell division. This is Li-Fraumeni syndrome (when p53 causes cancer from parents to offspring)
3.BRCA1
The parent that transmits mutation in one of these genes has a 50% chance of inheriting the mutation. The effects of mutations in BRCA2 and BRCA1 are seen when the person's second copy of the gene is normal.
Answer:
only females
Explanation:
In humans, sex chromosomes in males and females are different. The sex chromosomes found in humans are X and Y chromosomes. X-linked trait is a trait which is inherited on the X- chromosome. According to the question, the trait is passed on a X-linked dominant condition, which means the condition is inherited on the abnormal dominant X-chromosome that will express itself even when in an heterozygous state with a normal X-chromosome.
Hence, a father affected by the condition will have a genotype; XY while a mother that does not have the condition will have a genotype: xx (two normal x chromosomes). Since the Father can only pass his X chromosome to his daughters and never his sons, all his daughters will inherit the condition (see the punnet square in attached image).
N.B: None of the sons will inherit the condition since the mother will pass normal X-chromosomes (x) to her sons.
Answer: the answer is b
Explanation: i took the quiz