pH sacle may be defined as the scale that determines the pH of acids and bases. 0 represent the neutral compounds. The compounds that pH less than 7 acts as acid whereas the compounds that have pH greater than 7 acts as base.
Here, water is neutral, Hydrochloric acid (HCl) is acidic and sodium hydroxide (NaOH) acts as base.
It is sex-linked: genetic red-green color blindness affects males much more often than females, because the genes for the red and green color receptors are located on the X chromosome, of which males have only one and females have two.
In a mammalian brain, there are four major lobes that are present and one of them is the frontal lobe.
The frontal lobe is mainly rich in dopaminergic neurons and thus, it is mainly concerned with functions such as memory, reward, motivation, planning, attention, etc.
The process of break down of tissues and cell death in the tissues is referred to as atrophy and since the frontal lobe is associated with the functions as mentioned above its atrophy would lead to a slow decline in these functions.
Since Mr. Klondlike behavior is changing his blunt comments are most likely a result of atrophy of the frontal lobe.