In a given population system whereby the age-specific mortality rates can be estimated or determined, the best standardization method is the direct method. However, if the age-specific mortality rates of the given population system cannot be determined or estimated, the indirect standardization method should be applied.
bc if say they take meds for ADHD or ADD or depression so on if that shows up on the drug test that could be a potentional harm for what they are tryiong to acheive like sports or even a job